Retro+Virus

Retrovirus

= Sue: Publisher Julia: Researcher Cora: Researcher Michelle: Researcher Liz: Editor

Animations:
media type="youtube" key="dn1tNIrMPRk" height="390" width="480" align="center"

Another Animation {Click Here} =The Basic Life Cycle of a Retrovirus =
 * 1) The virus's life cycle starts in the infected nucleus. The retrovirus is covalently bonded to the DNA of the infected cell.
 * 2) =====Once the virus is successfully in the cell, the nucleoprotein complex finds the intracellular DNA nucleotide triphosphate pools, and a special enzyme called the reverse transcriptase protein creates a DNA copy of the virus to infect more cells later on. =====
 * 3) The new DNA finds a host strand of DNA to attach to, in another cell. It is now prepared to replicate, following step two, once again.

**Examples of a Retrovirus in Organisms**
-HIV/AIDS in humans  -Feline Leukemia -Hepatitis C in orangutans ===<span style="color: #008080; display: block; font-family: 'Comic Sans MS',cursive; font-size: 180%; line-height: normal; text-align: center; white-space: pre-wrap;">**Genus species Names of Organism Infected** === <span style="background-color: transparent; display: block; font-family: 'Comic Sans MS',cursive; font-size: medium; line-height: normal; text-align: center; white-space: pre-wrap;">-Homo sapiens sapiens (Humans) <span style="background-color: transparent; display: block; font-family: 'Comic Sans MS',cursive; font-size: medium; line-height: normal; text-align: center; white-space: pre-wrap;">-Felis catus (Cats) <span style="background-color: transparent; display: block; font-family: 'Comic Sans MS',cursive; font-size: medium; line-height: normal; text-align: center; white-space: pre-wrap;"> -Pongo borneo (Orangutans)

<span style="background-color: #ffffff; color: #008080; display: block; font-family: 'Comic Sans MS',cursive; font-size: 160%; font-style: normal; line-height: normal; text-align: center; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;">**Effect of Virus on O****rganism** ===<span style="background-color: transparent; color: #000000; font-family: 'Comic Sans MS',cursive; font-size: 11pt; font-style: normal; font-weight: normal; list-style-type: disc; text-decoration: none; vertical-align: baseline;">**<span style="background-color: transparent; color: #000000; font-size: 11pt; font-style: normal; text-decoration: none; vertical-align: baseline;">__Leukemia__- ** <span style="background-color: transparent; color: #000000; font-family: 'Comic Sans MS',cursive; font-size: 11pt; font-style: normal; text-decoration: none; vertical-align: baseline;">loss of appetite, poor condition of coat, skin infections, bladder and respiratory tract infections, seizures, swollen lymph nodes, fatigue, fever, weight loss, gingivitis, litter box avoidance, pancytopenia (condition when blood becomes dilute in red and white blood cells and platelets), poor grooming, reoccurring bacterial and viral illnesses, anemia, and diarrhea === ===<span style="background-color: transparent; color: #000000; font-family: 'Comic Sans MS',cursive; font-size: 11pt; font-style: normal; font-weight: normal; list-style-type: disc; text-decoration: none; vertical-align: baseline;">**__Hepatitis__-** <span style="font-family: 'Comic Sans MS',cursive;">**<span style="background-color: transparent; color: #000000; font-size: 11pt; font-style: normal; text-decoration: none; vertical-align: baseline;">Chronic (the stuff that keeps coming back): increased chance of liver cirrhosis, increased tendency to bruise and bleed, varices (enlarged veins, especially in the stomach and esophagus) ** === ===<span style="background-color: transparent; color: #000000; font-family: 'Comic Sans MS',cursive; font-size: 11pt; font-style: normal; text-decoration: none; vertical-align: baseline;">**Acute symptoms (the stuff that shows up after** the first six months): appetite, fatigue, abdominal pain, itching, and flu-like symptoms. === ===<span style="font-family: 'Comic Sans MS',cursive;">**<span style="background-color: transparent; color: #000000; font-size: 11pt; font-style: normal; list-style-type: circle; text-decoration: none; vertical-align: baseline;">__AIDS__- ** <span style="background-color: transparent; color: #000000; font-family: 'Comic Sans MS',cursive; font-size: 11pt; font-style: normal; font-weight: normal; list-style-type: circle; text-decoration: none; vertical-align: baseline;">**increased risk of developing various cancers, fevers, sweats (particularly at night), swollen glands, weakness, and weight loss** ===

=<span style="color: #008080; display: block; font-family: 'Comic Sans MS',cursive; text-align: center;">**Pictures of Organisms with and Without Virus:** = <span style="font-family: 'Comic Sans MS',cursive; line-height: 0px; overflow: hidden;">









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=<span style="color: #008080; display: block; font-family: 'Comic Sans MS',cursive; text-align: center;">**Annotated Bibliography** = "Feline Leukemia Virus." Cornell Veterinary Medicine. 11 Apr. 2011. <cornell.edu>. -provides information about Feline Leukemia ====<span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">"Human Retroviruses." <span style="color: #000000; font-size: 12pt; font-weight: normal; text-decoration: none; vertical-align: baseline;">//University of Cape Town.// <span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;"> 12 Apr. 2011. <web.uct.ac.za>. ====

<span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">- provides information about different kinds of retrovirus
<span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">"Life Cycle of HIV, a Retrovirus." <span style="color: #000000; font-size: 12pt; font-weight: normal; text-decoration: none; vertical-align: baseline;">//Sumanas// <span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">. 13 Apr. 2011. <sumanasinc.com> <span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">-provides information about HIV <span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">“Replication Cycle of a Retrovirus." <span style="color: #000000; font-size: 12pt; font-weight: normal; text-decoration: none; vertical-align: baseline;">//Microbiology.// <span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;"> 11 Apr. 2011. <highered.mcgraw-hill.com>. <span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">-provides retrovirus life cycle animation <span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">"retrovirus ." <span style="color: #000000; font-size: 12pt; font-weight: normal; text-decoration: none; vertical-align: baseline;">//YouTube// <span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">. 11 Apr. 2011. <youtube.com>. <span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">-provides animation of retroviruses <span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">"Retrovirus Life Cycle." <span style="color: #000000; font-size: 12pt; font-weight: normal; text-decoration: none; vertical-align: baseline;">//Stanford University// <span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">. 11 Apr. 2011. <stanford.edu>. <span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">-provides information about the life cycle <span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">"Viral pathogens." <span style="color: #000000; font-size: 12pt; font-weight: normal; text-decoration: none; vertical-align: baseline;">//MetaPathogen// <span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">. 13 Apr. 2011. <metapathogen.com>. <span style="color: #000000; font-size: 12pt; font-style: normal; font-weight: normal; text-decoration: none; vertical-align: baseline;">-provides information about pathogens